GETTING MY FRACTAL STORM (SELF-LAID TO WORK

In the LSD-sure crystal framework, the side chain with the lid residue L209EL2 sorts in depth hydrophobic contacts with both equally LSD and bordering residues in TMs III, IV, and V (Figure 4C). When the lid moved aside to show the binding pocket in simulation, quite a few of these contacts broke. We Hence hypothesized that L209EL2 acts like a latc